CDC Issues New Warning as Measles Cases Spike in the Midwest

Published on December 15, 2025

Vintage map of North America representing the nationwide scale of the measles outbreak.
The 2025 measles outbreak has spread across 43 jurisdictions, challenging the nation's public health infrastructure. Image: Pexels.

The Centers for Disease Control and Prevention (CDC) issued a stark warning today as measles cases continue to surge across several states in the American Midwest, a region previously less affected by the 2025 outbreaks. This new cluster of infections has raised alarms among public health officials, who fear that the nation's battle against the resurgent virus is expanding to new fronts.

According to the latest CDC data, over 150 new cases have been reported in the last two weeks across Ohio, Indiana, and Michigan, with smaller clusters emerging in Illinois and Wisconsin. This spike brings the total number of cases in the Midwest to 210 for the year. Health officials are particularly concerned about the rapid transmission in several Amish communities, where vaccination rates are traditionally low. The CDC's new warning urges clinicians in the region to be on high alert for measles symptoms and to immediately report any suspected cases to state health departments.

A Familiar Story: Low Vaccination and Community Spread

The pattern of the Midwest spike mirrors that of other major outbreaks in 2025: the virus is finding a foothold in undervaccinated populations. Public health investigations have traced the initial cases to international travel, but community transmission is now the primary driver of the spread. In one county in rural Ohio, kindergarten vaccination rates were as low as 65%, far below the 95% threshold needed for herd immunity.

State health departments are working with local community leaders and healthcare providers to increase vaccination uptake. Mobile vaccination clinics are being dispatched to rural areas, and public health campaigns are being launched to counter misinformation. However, officials face an uphill battle against entrenched vaccine hesitancy and a lack of trust in public institutions.

A National Threat Requires a National Response

The CDC is deploying additional resources to the affected states, including epidemiological support and communications assistance. The agency has reiterated its call for all Americans to ensure they are up-to-date on their MMR vaccinations. The Midwest spike is a sobering reminder that no community is immune to the threat of measles in the current environment of declining vaccination rates. As the nation heads into the winter months, when people spend more time indoors, the risk of transmission is expected to increase. The CDC's warning is a call to action for a renewed and unified national effort to stop the spread of this preventable disease.